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Genitourinary System

Benign Prostatic Hyperplasia (BPH) Medications

Tier 1 products are covered with no authorization necessary.

Tier 2 Prior Authorization criteria

  • FDA approved diagnosis.
  • Recent 4-week trial of at least two Tier 1 medications from different pharmacological classes within the last 90 days.
  • Documented adverse effect, drug interaction, or contraindication to all available Tier 1 products.

Tier 3 Prior Authorization Criteria

  • FDA approved diagnosis of BPH.
  • Trial of at least two Tier 1 medications from different pharmacological classes.
  • A 4-week trial of each Tier 2 medication within the past 5 months.
  • Documented adverse effect, drug interaction, or contraindication, or lack of efficacy to all available Tier 1 and Tier 2 products.
  • Authorizations for tadalafil (Cialis®) will be granted for 5mg tablets only.
Tier 1
Tier 2 Tier 3
  • alfuzosin (Uroxatrol®)
  • doxazosin (Cardura®)
  • finasteride (Proscar®)
  • tamsulosin (Flomax®)
  • terazosin (Hytrin®)
  • doxazosin (Cardura XL®)
  • dutasteride (Avodart®)
  • dutasteride/tamsulosin (Jalyn®)
  • silodosin (Rapaflo®)
  • tadalafil (Cialis®)
Bladder Control Drugs

Tier 1 products are covered with no authorization necessary.

Tier 2 Prior Authorization criteria

  • Trial of two Tier 1 medication that yielded inadequate clinical response or adverse effects, or
  • A unique FDA approved indication not covered by Tier 1 products.

Tier 3 Prior Authorization Criteria

  • Trial of all Tier 2 medications that yielded inadequate clinical response or adverse effects, or
  • A unique FDA approved indication not covered by lower Tiered products.
Tier 1
Tier 2 Tier 3
  • oxybutynin (Ditropan®)
  • trospium ER (Sanctura XR™)
  • oxybutynin ER tabs (Ditropan XL®)
  • tolterodine (Detrol®)
  • tolterodine ER tabs (Detrol LA®)
  • darifenacin (Enablex®)
  • oxybutynin Gel (Gelnique™)
  • mirabegron (Myrbetriq™)
  • oxybutynin patch (Oxytrol®)
  • trospium (Sanctura™)
  • fesoterodine (Toviaz™)
  • flavoxate (Urispas®)
  • solifenacin (VESIcare®)
*hyoscyamine can be used as adjuvant therapy only. By itself, it will not count as a tier 1 trial.
Miscellaneous Bladder Agents (Urelle®, Prosed DS®, Darpaz®)

Recent 14 day trials within the past 30-60 days of:

  • Urogesic Blue®, and
  • Utira-C®, Utrona-C®, or Darcalma®

If you have questions please call the Pharmacy Help Desk at (800) 522-0114 option 4 or (405) 522-6205 option 4.

Last Modified on Jul 12, 2021
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