The Oklahoma Department of Human Services Institutional Review (DHSIRB) was established to fulfill two obligations. First, it is tasked with protecting the rights and welfare of human participants involved in research. Second, it works to assist the investigator and the institution in their mutual obligation to comply with all applicable federal, state, and local laws, rules and regulations, including internal policies of the Department of Human Services, with respect to the research participants and investigators.
The DHSIRB is guided by the ethical principles regarding research involving human subjects set forth in the Belmont Report
which was created by the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The DHSIRB recognizes and strives to adhere to a set of research related principles identified within the Belmont Report. These include the respect for persons; beneficence, including the minimization of harms and maximization of benefits; and justice. In addition, all reasonable efforts are made to comply with the requirements in Part 46 of Title 45 of the Code of Federal Regulations for all research requiring DHSIRB approval.
The Institutional Review DHSIRB is responsible for reviewing and approving, requiring modifications to, or deferring approval of research involving human subjects associated with the Department of Human Services. Human subjects can include both clients and employees of the agency. The Board is also responsible for reviewing ongoing research activities on a continuing basis.
The DHSIRB is governed by Part 46 of Title 45 of the Code of Federal Regulations (45 C.F.R. 46). These regulations dictate the scope and purpose of the Board's activities. The Office for Human Research Protections (OHRP) is the federal agency that provides leadership in the efforts to protect the rights, welfare, and well-being of subjects involved in research conducted or supported by the U.S. Department of Health and Human Services.
The DHSIRB is registered with the U.S. Department of Health and Human Services as an Institutional Review Board.
The DHSIRB sought and received Federalwide Assurance of Protection for Human Subjects from the U.S. Department of Health and Human Services. The DHSIRB pledges to conduct its HHS-funded or – conducted research in compliance with 45 C.F.R. 46.